Futurama (2002) (TV)
- Starring as himself in "Where No Fan Has Gone Before"
- Futurama is a futuristic comedy cartoon created by Matt Groening, the same creator as The Simpsons. Futurama takes place in the year 3000, after a pizza delivery boy named Fry, is cryogenically frozen for 1,000 years. In the future he befriends Turanga Leela, the Cyclops mutant, and Bender, a drinking, swearing and stealing bending robot.
- In this episode, Fry is on trial for traveling to Omega 3 to retrieve all 79 episodes of "Star Trek". He sets out on his mission with Leela, Bender and Leonard Nimoy's head in a jar, only to discover William Shatner, Nichelle Nichols, George Takei and Walter Koening are living on Omega 3 under the watchful eye of Melllvar, an evil energy creature that's also their biggest fan.

American Psycho II: All American Girl (2002)
- Starring as Robert Starkman
- Rachael (Mila Kunis) is a college freshman that has survived an attack by serial killer Patrick Bateman. Now she forms an obsession with one of her professors, and, deciding that she must become his teaching assistant, begins to wipe out anyone who stands in her way.
- Robert Starkman is an ex-FBI agent and the leader of the university department for Behavioural and Social Sciences. He is Rachael's prefessor that she wants to become class assistant for.

Showtime (2002)
- Starring as himself / T.J. Hooker
- When LAPD detective Mitch Preston (Robert de Niro) shoots a news camera during a bust, the police chief orders him to work on a reality cop show, "Showtime" with LAPD Officer Trey Sellars (Eddie Murphy). The show is run by producer Chase Renzi (Rene Russo). Mitch and Trey are totally opposite and do not work well together at first.
Their first case is about a huge gun that can destroy a house. The TV show ends up being a hit.
- William Shatner as himself shows up in the movie when our three main characters are on the studio lot.

Miss Congeniality (2000)
- Starring as Stan Fields in both movies
- Sandra Bullock is the charmingly clumsy F.B.I. agent Gracie Hart. In the first of two movies, her office receives a letter from a terrorist going by the alias "The Citizen", they figure out that he's planning his next act at the Miss America beauty pageant. Because Hart is the only female officer at her office, she's chosen to go undercover as the contestant from New Jersey. She is given a full make-over and is trained by a man named Victor.
- Stan Fields is a pageant official.

3rd Rock from the Sun (1999-2000)
- Starring as The Big Giant Head/Stone Phillips
- 3rd Rock from the Sun was a comedy that looked at the absurdity of human behavior and society from the perspective of four alien beings that were on Earth to study mankind taking on human appearance to form the "Solomon" family.
- The Big Giant Head came to Earth to review the team's results and performance, but was quickly distracted by the vices his new flesh afforded. He got Vicki Dubchek pregnant and left after she discovered that she was pregnant. The Big Giant Head would return twice, the first was to take Vicki and child back with him and the next time he revealed that he was Dick's father, making Dick's full name Dick Head. During a couple of his appearances there were some Twilight Zone jokes related to the episode "Nightmare at 20,000 Feet." that Shatner also appeared in.

Free Enterprise (1998)
- Starring as Bill
- Two filmmakers, obsessed with Star Trek, look to William Shatner for some advice on their lives.

The Fresh Prince of Bel-Air (1996) (TV)
- Starring as Himself in "Eye, Tooth"
- The show was about Rapper/actor Will Smith who was shipped out to California to live with wealthy relatives. He teaches his new family some street smarts, while he tries to learn some old-fashioned beliefs and values. His Aunt Vivian and Uncle Philip can't control him, and he attempts to get everyone else to fit in around him, including cousins Carlton), Hilary, and Ashley.
- William Shatner stars as Hilary's talk-show guest, but Will must find a way to beam him from the dentist's chair to the set.